Effect of Vanzacaftor/Tezacaftor/Deutivacaftor (VNZ/TEZ/D-IVA) on the PK of Rosuvastatin in Healthy Participants

Completed · Phase 1

Conditions studied: Cystic Fibrosis

In brief

The purpose of this study is to evaluate the effect of multiple doses of vanzacaftor/tezacaftor/deutivacaftor (VNZ/TEZ/D-IVA) on the PK of rosuvastatin and the safety and tolerability of coadministration of VNZ/TEZ/D-IVA with rosuvastatin.

Key facts

Study ID
NCT07349394
Run by
Vertex Pharmaceuticals Incorporated
People needed
18
Starts
2026-01-12
Expected to finish
2026-03-12
Last updated by the study team
2026-04-02

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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