Early Effects of Orthognathic Surgery on Periodontal Phenotype: A 6-Month Prospective Clinical and Radiographic Evaluation

Recruiting now

Conditions studied: Gingival Biotype, Gingival Phenotype, Buccal Bone Thickness, Recession, Gingival, Dental Surgery

In brief

The goal of this observational study is to learn how the health and thickness of the gums and supporting bone around the teeth change over 6 months in adults having jaw surgery to correct the bite. The main questions it aims to answer are: * Do gum and tooth-support measurements change from before surgery to 1, 3, and 6 months after surgery? * Do CT scan-based measurements of the tooth-supporting bone change over the same time period? Participants will: * Have a gum check-up (periodontal examination) before surgery and at 1, 3, and 6 months after surgery. * Have CT scan-based measurements (CBCT) taken at the same time points for study assessment.

Key facts

Study ID

NCT07349056

Run by

Trakya University

People needed

100

Starts

2026-02-23

Expected to finish

2027-02-23

Last updated by the study team

2026-06-08

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged ≥18 years.
• Presence of a Class III molar relationship of any severity at baseline.
• Presence of a Class II molar relationship of any severity at baseline.
• Presence of transverse arch discrepancies.
• Presence of vertical maxillary excess.
• Presence of maxillary and/or mandibular asymmetry.
• Presence of anterior open bite.
• Full permanent dentition up to the first molars, with no supernumerary teeth and no agenesis (congenital absence) of teeth up to the first molars.
• No previous orthodontic treatment.
• No history of tooth extraction other than second or third molars.
• Availability of complete baseline and end-of-follow-up periodontal parameters and phenotype records suitable for evaluation.
• Healthy periodontium with no signs of gingival hypertrophy.
• No systemic disease history or medication use that could affect gingival/periodontal conditions.

You may not qualify if…

• Patients planned for orthodontic camouflage treatment with fixed appliances for Class II/Class III correction instead of orthognathic surgery.
• History of interproximal enamel reduction (interproximal stripping).
• Presence of dental implants.
• Age < 18 years.
• Pregnant or breastfeeding individuals.
• Any systemic condition contraindicates orthognathic surgery.
• Psychiatric disorders.
• Syndromic conditions.
• History of previous orthognathic surgery.
• Refusal to sign the informed consent form.
• Individuals belonging to a vulnerable population.

Where it is running

• Trakya University Faculty of Dentistry — Edirne, Turkey (Türkiye) (enrolling)
• Kocaeli Health and Technology University Faculty of Dentistry — Kocaeli, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.