Effects of DHA in Patients With Multiple Sclerosis
Enrolling by invitation · Not applicable · Has a placebo group
Conditions studied: Multiple Sclerosis, Performance Enhancement, Supplemental Nutrition Assistance Program Education, Strength Outcomes, Function Improvement, Intervention Study
In brief
This clinical trial will investigate the effects of combining therapeutic exercise with DHA supplementation in 100 patients with multiple sclerosis using a randomized controlled design. Participants, diagnosed according to the McDonald criteria, will undergo functional, cognitive, fatigue, and quality-of-life assessments through tools such as the EDSS, BRB-N, MFIS, EVA-f, and MSQoL-54. Physiological evaluations will include infrared thermography, isokinetic strength testing, perceived exertion (Modified Borg Scale), balance (Timed Up and Go), lower-limb power (Sit-to-Stand app), and handgrip strength. The study hypothesizes that this combined intervention will improve motor function, cognition, fatigue management, and overall quality of life by enhancing neuromuscular activation and metabolic efficiency.
Key facts
- Study ID
- NCT07346703
- Run by
- Francisco Javier Martínez Noguera
- People needed
- 100
- Starts
- 2026-01-01
- Expected to finish
- 2026-07-01
- Last updated by the study team
- 2026-01-16
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- The patient sample comes from the Multiple Sclerosis Association (AMDEM) of the Murcia region and the neurology department of the Ribera Salud Hospital in Molina de Segura. Patients diagnosed with multiple sclerosis according to the McDonald criteria, aged between 18 and 65 (approximately), who have not suffered any flare-ups in the previous month and who have a score of 0.00 to 6 on the Expanded Disability Status Scale (EDSS) and are able to activate the tibialis anterior muscle will be eligible for the study.
You may not qualify if…
- Not fulfilling the inclusion criteria.
- Having any problems performing the tests.
- Having any problems taking the supplement or placebo.
Where it is running
- Research Center for High Performance Sport. Universidad Católica de Murcia — La Ñora, Murcia, Spain
Full record on ClinicalTrials.gov
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