Basilar Artery Occlusion Chinese Endovascular Registry in Patients With Large-Core Infarct
Recruiting now
Conditions studied: Basilar Artery Occlusion, Ischemic Stroke, Large Core Infarct
In brief
This multicenter retrospective registry study evaluates the safety and effectiveness of endovascular therapy versus medical therapy for acute large-core basilar artery occlusion. It also investigates clinical, imaging, and laboratory factors associated with functional outcomes and mortality. Patients are grouped according to the treatment received in routine clinical practice.
Key facts
- Study ID
- NCT07345702
- Run by
- Xuanwu Hospital, Beijing
- People needed
- 518
- Starts
- 2026-01-31
- Expected to finish
- 2026-10-31
- Last updated by the study team
- 2026-07-30
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age ≥18 years, men or women.
- Occlusion (TIMI 0-1) of the basilar artery or intracranial segments of both vertebral arteries (V4) as evidenced by CTA/MRA/DSA.
- Time from symptom onset (or last known well) to treatment (endovascular therapy or medical therapy) ≤7 days.
- Patients with large core infarction in the posterior circulation, defined as a posterior circulation Acute Stroke Prognosis Early CT score (pc-ASPECTS) score of 0-5 on CT angiography source images or MR with diffusion-weighted imaging or non-contrast CT.
You may not qualify if…
- Subjects with occlusions in both anterior and posterior circulation.
- CT or MR evidence of hemorrhage (the presence of microbleeds on MRI is allowed).
- Missing key clinical information (e.g., unavailable baseline NIHSS, unclear symptom onset/last known well time, or missing major treatment information including whether EVT was performed).
- Baseline NIHSS score <6.
- Woman of childbearing potential who is known to be pregnant or lactating or who has a positive pregnancy test on admission.
- Missing follow-up outcomes at 90 days.
- Any other condition judged by investigators to substantially affect analysis or interpretation.
Where it is running
- Xuanwu Hospital — Beijing, Beijing Municipality, China (enrolling)
Full record on ClinicalTrials.gov
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