Stimulus Equivalence Learning in Acquired Brain Injury.
Recruiting now
Conditions studied: Acquired Brain Injury (Including Stroke)
In brief
Stimulus Equivalence Learning (SEL) is a form of learning in which stimuli (such as words, pictures, or sounds) become linked to one another in memory, even though this specific connection has not been directly taught. In a typical SEL task, two relations are taught explicitly (A→B and A→C), and the untrained relation (B→C) is then tested. This indirect relation is not intentionally or consciously learned and is considered a form of implicit learning. The principle of stimulus equivalence learning is still rarely applied in cognitive rehabilitation after acquired brain injury (ABI), with the exception of a few small (N=1) treatment studies that have shown positive effects. However, it remains unclear to what extent ABI may affect the ability to acquire stimulus equivalence.
Key facts
- Study ID
- NCT07345481
- Run by
- Klimmendaal Revalidatiespecialisten
- People needed
- 40
- Starts
- 2026-01-29
- Expected to finish
- 2026-07-01
- Last updated by the study team
- 2026-05-22
Who can join
Age: 18 and older, up to 75. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- ABI patients (>3 months post-injury), including stroke, traumatic brain injury, brain tumor, encephalitis, and out-of-hospital cardiac arrest (OHCA).
You may not qualify if…
- Neurodegenerative disorders Severe psychiatric disorders (including suicidality) Insufficient command of the Dutch language Severe cognitive impairments, aphasia, or visual or hearing problems that make test administration impossible
- An additional exclusion criterion for controls was any medical condition that could lead to cognitive impairment beyond normal aging, including stroke, TBI, brain tumor, or other forms of brain injury.
Where it is running
- Klimmendaal Revalidatiespecialisten — Arnhem, Gelderland, Netherlands (enrolling)
Full record on ClinicalTrials.gov
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