Clinical Trial to Assess the Efficacy and Safety of a Cosmetic Product in Individuals Showing Signs of Cutaneous Aging.

Starting soon · Not applicable

Conditions studied: Skin, Skin Ageing, Fine Lines, Face Aging/Photo Aging of Moderate Grade, Face Skin Photoaging

In brief

This clinical study investigates the effects and safety of a topical cosmetic product containing postbiotics (Bifida ferment extract and Pediococcus ferment extract) in women aged 35-60 with visible signs of skin aging. The study is a 3-month, single-center, intra-subject controlled trial involving 45 Caucasian women with sensitive or normal skin. Participants will apply 1 ml of the product twice daily. Clinical evaluations will be conducted at baseline and at 1 month, 2 months, and 3 months, using validated dermatological scales and non-invasive instruments (AEVA3D, Mexameter®, MoistureMap®, Cutometer®, Tewameter®, Clarius®, Glossymeter®). Safety will be assessed through systematic monitoring of adverse events, with serious adverse events expected to remain below 1%. Subjective perception will be evaluated via structured questionnaires.

Key facts

Study ID: NCT07343544
Run by: AB Biotics, SA
People needed: 45
Starts: 2026-02-01
Expected to finish: 2026-05-01
Last updated by the study team: 2026-01-15

Who can join

Age: 35 and older, up to 60. Sex: female. Healthy volunteers: accepted.

You may qualify if…

Female participants.
Age between 35 and 60 years.
All skin types (combination, oily, dry, and/or normal).
Skin condition: 50% sensitive skin and 50% normal skin.
Visible signs of facial skin aging (mild/moderate wrinkles and/or pigmentation spots).
Willingness to participate voluntarily and provide written informed consent.
Ability to understand the study objectives and procedures.
Good general health (physical and mental).
Availability to attend all scheduled visits at the research center.
Discontinuation of anti-aging products on the experimental area (face) at least 7 days prior to study start.
Commitment not to change facial hygiene routines during the study.

You may not qualify if…

Pregnant or breastfeeding women.
History of allergy to cosmetic products and/or dietary supplements.
Known allergy or hypersensitivity to any component of the product.
History or current diagnosis of cancer.
Active skin diseases or infections in the experimental area.
Recent or planned surgical or aesthetic interventions in the experimental area Medical-aesthetic treatments on the face within the last 6 months (e.g., botulinum toxin, hyaluronic acid, laser, radiofrequency, HIFU, deep chemical peels, microneedling with actives).
Relevant dermatological conditions in the experimental area (eczema, psoriasis, allergic/contact dermatitis, etc.).
Use of topical or systemic medications affecting the skin (retinoids, antibiotics, corticosteroids) within the last 3 months.
Current or planned use of supplements that may affect skin health (collagen, antioxidant vitamins A/C/E, zinc, omega-3, oral probiotics/prebiotics).
Systemic diseases such as autoimmune disorders (rheumatoid arthritis, lupus, multiple sclerosis), chronic viral infections (HIV, hepatitis B/C), or severe metabolic diseases.
Use of any product other than the study product on the experimental area during the study.
Planned significant changes in health habits during the study (diet, physical activity, structured exercise programs).
Recent or planned changes in hormonal contraceptives.
Sun or UVA exposure during the study.
Participation in another clinical study involving the same experimental area
Application of any product on the experimental area on the day of study initiation.
Any medical condition, at the investigator's discretion, that may interfere with protocol adherence or participant safety.

Full record on ClinicalTrials.gov

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