Dual-energy CT vs. MRI in the Evaluation of Squamous Cell Carcinomas of the Oral Cavity and Oropharynx

Recruiting now

Conditions studied: Oral Squamous Cell Carcinoma, Oropharyngeal Squamous Cell Carcinoma

In brief

The diagnostic and pre-therapeutic assessment of squamous cell carcinomas requires a neck and chest CT scan and a neck and facial MRI, which is the most effective examination, to establish the TNM stage of the tumor. However, obtaining this complete assessment can delay treatment. Confirmation of the non-inferiority of 40keV dual-energy CT in BOLT compared to MRI would spare the patient an additional MRI examination, speed up the pre-treatment assessment, reduce the loss of opportunity due to delayed treatment, and free up MRI imaging slots, which are still insufficient in the region.

Key facts

Study ID

NCT07343271

Run by

University Hospital, Strasbourg, France

People needed

30

Starts

2025-07-11

Expected to finish

2026-07-11

Last updated by the study team

2026-01-15

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patient (≥18 years)
• presenting with oral or oropharyngeal squamous cell carcinoma proven by histopathological analysis of a biopsy
• having undergone a clinical examination with nasofibroscopy by an ENT surgeon specializing in cancer surgery
• a contrast-enhanced cervicofacial MRI
• and a contrast-enhanced cervicofacial DECT with BOLT maneuver.

You may not qualify if…

• A lesion other than oral or oropharyngeal squamous cell carcinoma
• A labial location
• A contraindication to performing one or both of the imaging examinations.

Where it is running

• Service d'ORL et de Chirurgie Cervico-faciale - CHU de Strasbourg - France — Strasbourg, France (enrolling)

Full record on ClinicalTrials.gov

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