The Rhinovirus Hospitalization and Investigation of Nasal-airway Omics (RHINO) Study

Recruiting now

Conditions studied: Rhinovirus

In brief

The goal of this study is to determine the burden of Rhinoviruses (RVs) as a cause of acute, severe, respiratory illnesses leading to hospitalization. A community cohort of 120 children between 12 and 36 months of age will be enrolled in the first year of the study and followed (when well and sick) for 36 months to identify the circulating RVs and provide samples to establish a host nasal transcriptome differentiating clinical from subclinical RV infections. A hospitalized cohort of 450 infants and children will be enrolled during years 1 through 3 of the study and followed for the duration of their hospitalization to investigate the findings of the community cohort. An additional 100 healthy children aged 5-17.5 years will be enrolled for age-match comparison with the older hospitalized cohort.

Key facts

Study ID
NCT07342582
Run by
University of Wisconsin, Madison
People needed
670
Starts
2026-08-01
Expected to finish
2030-05-01
Last updated by the study team
2026-07-23

Who can join

Age: any, up to 17. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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