Effects of Vitamin B12 and Natural Orange Extract, and Their Combination on Physical and Mental Performance

Enrolling by invitation · Not applicable · Has a placebo group

Conditions studied: Vitamin b12, Supplementation During Endurance Performance, Flavonoids, Mental Fatigue, Biomarker Feedback

In brief

The aim of this study was to determine the effects of a new formulation of vitamin B12, natural orange extract, and their combination on physical and mental performance.

Key facts

Study ID

NCT07341789

Run by

Francisco Javier Martínez Noguera

People needed

20

Starts

2025-12-01

Expected to finish

2026-06-01

Last updated by the study team

2026-01-14

Who can join

Age: 18 and older, up to 45. Sex: male. Healthy volunteers: accepted.

You may qualify if…

• Healthy male (to be certified through medical examination and health analysis).
• Aged 18-45 years.
• Well-trained (3-6 training sessions per week).
• Habitual consumer of citrus fruits (orange, mandarin, lemon, or grapefruit, either fresh or juiced).

You may not qualify if…

• Smokers or regular alcohol drinkers.
• Persons suffering from a metabolic, cardiorespiratory or digestive pathology or anomaly.
• digestive system.
• People who have suffered an injury in the last 6 months that limits the performance of the study tests. of the study tests.
• People taking supplements or medication in the 2 weeks before the start of the study.

Where it is running

• Research Center for High Performance Sport. Universidad Católica de Murcia — La Ñora, Murcia, Spain

Full record on ClinicalTrials.gov

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