Steroid Use in Treatment of Allergic Reactions to Food
Recruiting now · Phase 4
Conditions studied: Anaphylactic Reaction, Anaphylaxis, Allergy in Children, IgE Mediated Food Allergy
In brief
In this study, the investigators want to find out whether a specific medication commonly used for severe allergic reactions is really necessary. When children have allergic reactions to foods, they are often given medications to relieve the symptoms. In addition to adrenaline and antihistamines, steroids are frequently administered in German-speaking Switzerland. However, it is unclear whether steroids are really helpful in this situation. To investigate this, the investigators are comparing two groups: one group receives additional steroids, and the other does not. Which treatment a participant receives is decided randomly, like flipping a coin. The study takes place during a pre-scheduled provocation test at the clinic. If an allergic reaction occurs, the usual emergency medications will be administered. Doctors will closely monitor how the reaction develops. No additional tests or visits are required. The results of this study could help improve allergy treatment in the future.
Key facts
- Study ID
- NCT07341776
- Run by
- Johannes Trueck
- People needed
- 160
- Starts
- 2026-01-26
- Expected to finish
- 2026-12-01
- Last updated by the study team
- 2026-01-27
Who can join
Age: 1 and older, up to 18. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- suspected or confirmed IgE-mediated food allergy
You may not qualify if…
- Non-IgE mediated food allergies
- Non-food allergies
- Age outside the specified range
- Contraindications for an oral food challenge or oral steroid use within one week before the challenge.
Where it is running
- University Children's Hospital Basel — Basel, Basel, Switzerland (enrolling)
- University Children's Hospital, Zürich — Zurich, Canton of Zurich, Switzerland (enrolling)
Full record on ClinicalTrials.gov
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