Long-term Adaptations of Skeletal Muscle After Hybrid Training
Recruiting now · Not applicable
Conditions studied: Obesity & Overweight
In brief
Obesity is a major challenge for public health and renders it imperative to reduce its prevalence. High intensity interval training (HIIT) is a form of exercise training that can efficiently induce weight loss in adults with overweight or obesity, even in the absence of dietary intake manipulation. Hybrid type training represents a form of HIIT, that incorporates both cardiorespiratory and musculoskeletal stimuli, by combining multiple types of exercise into a circuit-type, interval style workout. Recent evidence suggests that long-term participation in hybrid HIIT results in significant health-related benefits. However, the molecular mechanisms driving the chronic effects of hybrid HIIT on cardiometabolic and musculoskeletal health remains to be elucidated.
Key facts
- Study ID
- NCT07341711
- Run by
- University of Thessaly
- People needed
- 30
- Starts
- 2026-01-08
- Expected to finish
- 2026-12-20
- Last updated by the study team
- 2026-06-12
Who can join
Age: 30 and older, up to 50. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- BMI: >25 kg/m2 and <40 kg/m2
- Untrained individuals (abstain >1 year from exercise training)
- No dietary intervention over the last 6 months preceding the study
- Low cardiorespiratory fitness level (VO2max: <45 ml/kg/min)
- No use of any medication, dietary supplements
- Low risk for cardiovascular disease
- A weight loss <10% over the last 6 months preceding the study
- Free of non-communicable diseases (excluding metabolic syndrome)
You may not qualify if…
- Low participation rate (<80% completion of the exercise training sessions)
- Unbalanced diet
- Participation in additional exercise training regimes
- Cosumption of anti-inflammatory of pain relief medication
Where it is running
- Department of Physical Education and Sport Science Trikala, University of Thessaly — Trikala, Thessaly, Greece (enrolling)
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.