Worldwide Assessment of Deceased Donor Kidney Utilization
Enrolling by invitation
Conditions studied: Kidney Failure, Kidney Transplant, Deceased Donor Kidney Transplant
In brief
The persistent imbalance between kidney transplant demand and organ availability remains a major global challenge. Optimizing the utilization of kidneys from deceased donors is a critical strategy to expand the donor pool and increase access to transplantation. Previous studies have demonstrated substantial international differences in kidney acceptance and discard practices, with significant potential gains in allograft life-years through optimized utilization. However, major changes in allocation policies, donor characteristics, preservation technologies, and global events such as the COVID-19 pandemic may have altered contemporary utilization patterns. This study aims to characterize international trends in deceased donor kidney utilization, compare allograft survival across countries, and estimate potential transplantable allograft life-years gained through improved utilization practices.
Key facts
- Study ID
- NCT07341516
- Run by
- Paris Translational Research Center for Organ Transplantation
- People needed
- 300000
- Starts
- 2025-11-01
- Expected to finish
- 2026-11-01
- Last updated by the study team
- 2026-01-14
Who can join
Age: any. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- All consecutive kidneys recovered for the purpose of transplantation from donors deceased from brain death or circulatory death between January 1, 2010 and December 31, 2025
You may not qualify if…
- Kidneys offered to transplant centers but never recovered
- Living renal transplants
- Multiorgan transplant recipients
Where it is running
- Vanderbilt Center for Transplant Science, Vanderbilt University Medical Center, Nashville, TN, USA — Nashville, Tennessee, United States
- Paris Institute for Transplantation and Organ Regeneration, INSERM, UMR-S970, Paris, France — Paris, France
Full record on ClinicalTrials.gov
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