Sensory Mechanisms of Manual Dexterity Recovery After Stroke: a Prospective Cohort Study of Prediction and Cerebral Correlates

Starting soon · Not applicable

Conditions studied: Stroke, Upper Extremity Paresis, Manual Dexterity, Sensory Integration Dysfunction, Vibration

In brief

In the proposed research, we will assess motor and sensory functions of the hand using clinical tests and a tool designed to measure manual dexterity combined with vibrotactile stimulation. We will also evaluate the integrity of brain structure and function using MRI.

Key facts

Study ID

NCT07340736

Run by

Centre Hospitalier St Anne

People needed

90

Starts

2026-03-01

Expected to finish

2028-03-01

Last updated by the study team

2026-01-14

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• First symptomatic stroke, ischaemic or haemorrhagic in the early subacute phase (up to 3 weeks post-stroke)
• Upper limb paresis (≤4/5 MRC Scale)
• Ability to grasp, lift and put down 1 block (from the BBT test)
• Be affiliated to a social security

You may not qualify if…

• Presence of another neurological or musculoskeletal condition affecting upper limb movement
• Severe cognitive impairment and/or aphasia with inability to understand and carry out instructions
• Contraindications to MRI (claustrophobia, presence of cochlear implants and/or pacemakers)
• Persons subject to legal protection measures
• Persons subject to judicial protection measures
• Pregnancy
• Life-threatening conditions or conditions requiring follow-up at 6 months
• Epilepsy
• Known hypersensitivity or allergy to silicone

Where it is running

• GHU Psychiatrie et Neurosciences — Paris, France

Full record on ClinicalTrials.gov

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