Fluid Balance in Acute Kidney Injury in Critically Ill Patients

Starting soon

Conditions studied: Fluid Balance, Acute Kidney Injury, Critically Ill Acute Kidney Injury, Critically Ill

In brief

This prospective observational cohort study evaluates if fluid balance in the first 48 hours of ICU admission is linked to acute kidney injury (AKI) in critically ill adults. Patients without AKI at entry will have fluids tracked hourly via charts, weights, and labs to assess AKI risk by KDIGO criteria within 7 days. Findings may guide better fluid management to lower AKI rates.

Key facts

Study ID

NCT07338734

Run by

Assiut University

People needed

120

Starts

2026-01-01

Expected to finish

2027-02-01

Last updated by the study team

2026-01-14

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged 18 years or older admitted to the ICU.
• Patients with no AKI at ICU admission.
• AKI secondary to (prerenal cause-renal and post renal with manifestation of hypovolemia)-postoperative settings-On top of CKD up to Stage 111b-Compansated heart failure with indication of fluid therapy

You may not qualify if…

• Patients with pre-existing end-stage renal disease requiring dialysis.
• Patients with known chronic kidney disease stage 4 or higher.
• ICU readmissions during the same hospitalization.
• Patients who received renal replacement therapy before ICU admission
• Patients with AKI with manifestation of over load as pulmonary edema- pulmonary embolism-Acute decompensated heart failure

Full record on ClinicalTrials.gov

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