Multimodal Cardiovascular Magnetic Resonance Imaging for Cardiometabolic Pre-HF and HFpEF
Enrolling by invitation
Conditions studied: Diabetes (DM), Hypertension, Heart Failure, Obesity & Overweight
In brief
This is an observational study aiming to characterize the pathophysiological features and clinical significance of cardiometabolic early-stage heart failure using advanced multimodal cardiovascular magnetic resonance (CMR) imaging. The study will focus on patients with cardiometabolic risk factors such as diabetes, hypertension, and obesity who are in the pre-heart failure (pre-HF) stage or have heart failure with preserved ejection fraction (HFpEF). The study seeks to establish a full-chain imaging framework-from precise phenotypic classification and sensitive noninvasive diagnosis to individualized cardiovascular risk stratification. Participants will undergo multimodal CMR scans and comprehensive clinical evaluations and be followed up for primary outcome.
Key facts
- Study ID
- NCT07336316
- Run by
- Chinese Academy of Medical Sciences, Fuwai Hospital
- People needed
- 3000
- Starts
- 2010-01-01
- Expected to finish
- 2030-12-31
- Last updated by the study team
- 2026-01-23
Who can join
Age: any. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Left ventricular ejection fraction (LVEF) ≥ 50%；
- Presence of cardiovascular risk factors, including, but not limited to, the following: diabetes mellitus, hypertension, obesity.
You may not qualify if…
- Primary cardiomyopathy (e.g., hypertrophic, dilated, and restrictive cardiomyopathy)
- Acute coronary syndrome in the previous 30 days
- More than moderate valvular disease
- Restrictive pericardial disease
- Severe arrhythmia
- Heart tumors
- Infiltrative cardiomyopathy (e.g., cardiac amyloidosis)
- Congenital heart disease
- Poor image quality insufficient for delineating the endocardium and epicardium
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.