TROPIS Versus Coring Out Fistulectomy in High Anal Fistula

Recruiting now · Not applicable

Conditions studied: High Anal Fistula

In brief

High anal fistulas represent a surgical challenge due to high recurrence rates and risk of postoperative fecal incontinence. Several sphincter-preserving techniques have been developed to address these issues. Coring Out fistulectomy is a traditional sphincter-saving approach, while Transanal Opening of the Intersphincteric Space (TROPIS) is a recently introduced technique with promising outcomes. This randomized clinical trial aims to compare the efficacy, safety, and patient outcomes of TROPIS versus coring out fistulectomy in the management of high complex anal fistulas.

Key facts

Study ID

NCT07334678

Run by

Cairo University

People needed

64

Starts

2025-07-08

Expected to finish

2026-06-01

Last updated by the study team

2026-05-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients with high anal fistula ( involving more than 1/3 of the sphincter complex), whether de novo or recurrent

You may not qualify if…

• Patients with fistula secondary to malignancy, inflammatory bowel disease, trauma or radiation
• Patients with Low anal fistula
• Patient with preoperative fecal incontinence
• Previous levator ani muscle injury

Where it is running

• Faculty of medicine Cairo University — Cairo, Al-Manial Cairo, Egypt (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.