Emotional Well-being and Measures of Healthy Aging

Recruiting now · Not applicable

Conditions studied: Aging, Aging, Healthy, Aging Well, Aging, Biological

In brief

This randomized control study is designed to understand the role of a positive psychology intervention (PARK: Positive Affect Regulation sKills) in biological aging and well-being. PARK provides a series of positive emotion skills in a self-guided online format, making the program accessible and convenient. Our main aims are: Aim 1: To explore the effects of PARK on psychological well-being (e.g., depression, anxiety, positive affect). Aim 2: To explore the effects of PARK on biological age as defined by DNA methylation (DNAm) GrimAge and electrocardiogram-age (ECG-age), as well as physiological well-being in adults (e.g., cardiovascular, endocrine, musculoskeletal functioning, etc.).

Key facts

Study ID

NCT07334106

Run by

Northwestern University

People needed

80

Starts

2025-09-01

Expected to finish

2028-08-01

Last updated by the study team

2026-01-12

Who can join

Age: 40 and older, up to 70. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 40-70
• Speaks and reads English
• Able to access the online platform through their phone, a public device (i.e., at the library) or at home.
• Lives in the Chicagoland area
• Willing/able to travel to the Human Longevity Lab for in-person visits

You may not qualify if…

• Adults unable to consent
• Individuals who are not yet adults (infants, children, teenagers)
• Pregnant women
• Prisoners
• Vulnerable Populations
• Pre-existing heart disease (prevalent coronary heart and cerebrovascular disease or heart failure)
• Type 2 diabetes
• Severe psychiatric illness

Where it is running

• Potocsnak Human Longevity Lab — Chicago, Illinois, United States (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.