Effect of Intravenous Dexmedetomidine and Ketamine on Post-Operative Analgesia

Starting soon · Phase 3 · Has a placebo group

Conditions studied: Postoperative Analgesia, Postoperative Pain Management

In brief

In this study the participants aim to Compare The Effect of Intravenous Combination Dexmedetomidine \_ Ketamine versus Dexmedetomidine on Post-Operative Analgesia In Vaginal Hysterectomy Proceeded Under Spinal Anesthesia regarding efficacy, hamemodynamic stability, outcomes and adverse effects.

Key facts

Study ID

NCT07330375

Run by

Zagazig University

People needed

50

Starts

2026-01-20

Expected to finish

2026-06-30

Last updated by the study team

2026-01-09

Who can join

Age: 21 and older, up to 65. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• Patients who will accept written informed consent.
• Age: 21-65 years old.
• Sex: female.
• BMI: <35 kg/m2
• Physical status: American Society of Anesthesiology (ASA) of Grade I-II
• Type of operation: vaginal hysterectomy under spinal anesthesia.

You may not qualify if…

• Uncooperative patients
• Any contraindication for spinal anesthesia e.g. coagulopathy, infection at site of block, and hypersensitivity to any drug used in this study.
• Patients who are known to be drug dependent.

Full record on ClinicalTrials.gov

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