Retention of Pits and Fissure Sealants on Non Carious vs Initial Carious Enamel Lesions in Posterior Teeth

Recruiting now

Conditions studied: Dental Enamel, Dental Enamel Hypomineralization, Dental Enamel Hypoplasia

In brief

This clinical study is planned to be conducted to compare retention rates of pits and fissure sealants on non carious (ICDAS score 0) vs Initial carious enamel lesions (ICDAS Score 1,2) in posterior permeant teeth at 3 months, 6 months and 12 months follow-up. This will help us guide follow-up strategies for optimal caries prevention.

Key facts

Study ID

NCT07330089

Run by

Foundation University Islamabad

People needed

420

Starts

2025-12-27

Expected to finish

2027-06-30

Last updated by the study team

2026-05-26

Who can join

Age: 7 and older, up to 18. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Fully erupted maxillary and mandibular 1st and 2nd molars with antagonist teeth present.
• ICDAS score 0,I,II
• Age 7 to 18 years
• Both genders included

You may not qualify if…

• permanent teeth requiring restorations,
• uncooperative patients
• patients unwilling for follow-ups
• molars withy antagonist teeth not present
• mentally and physically handicapped patients
• patients with parafunctional habits
• patients undergoing orthodontic treatments

Where it is running

• Foundation University Islamabad — Islamabad, Federal, Pakistan (enrolling)

Full record on ClinicalTrials.gov

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