Comparing Tear Proteomics Profile in Dry Eye Disease pre-and Post-treatment With Low Level Light Therapy
Recruiting now
Conditions studied: Dry Eye, Meibomian Gland Dysfunction (Disorder)
In brief
The purpose of this research study is to understand the mechanism of action of low level light therapy and also potentially yield markers associated with good treatment response. Low-level light therapy is light-based treatment delivered through advance eye-light device. This therapy uses light energy to provide energy to the meibomian gland cells to slow down age-ing, improve tear stability and reduce inflammation.
Key facts
- Study ID
- NCT07329712
- Run by
- Singapore National Eye Centre
- People needed
- 30
- Starts
- 2025-11-05
- Expected to finish
- 2027-12-31
- Last updated by the study team
- 2026-01-09
Who can join
Age: 21 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Must be eligible for, and have consented for low level light therapy
- Must not have presented to the clinic for an acute eye problem such as visual loss or painful eye
- Ability to give informed consent.
- Age more or equals to 21 years old.
You may not qualify if…
- Patients who are unable to or decline to give consent.
- Age less than 21 years old.
- Patients who presented to the clinic for an acute eye problem such as visual loss or painful eye.
- Patients not suitable for low level lighttherapy:
- Pregnant
- Fitted with pacemakers, metal, electrical, acoustic prosthetics
- Epilepsy, cardiac rhythm or frequency disorders
- Fever, thrombophlebitis or acute phlebitis of the legs, large-sized varicose veins, or venous surgery within 2 months
- Uncontrolled hypertension or severe diabetes
- Open wounds on eyelid or skin
- Evolving cancer or hepatitis
- Blood anticoagulant or coagulation defect
Where it is running
- Singapore Eye Research Insititute — Singapore, Singapore (enrolling)
Full record on ClinicalTrials.gov
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