Postoperative Ozonated Oil Dressing After Open Inguinal Hernia Repair: A Randomized Pilot Trial

Recruiting now · Not applicable

Conditions studied: Inguinal Hernia Unilateral, Postoperative Wound Inflammation

In brief

This study looks at whether a special wound dressing containing ozonated oil can reduce early wound inflammation after open inguinal hernia surgery. Open inguinal hernia repair is a common operation, and although infection rates are low, many patients experience redness, swelling, tenderness, or discomfort at the surgical site during the first days after surgery. Participants undergoing elective open inguinal hernia repair will be randomly assigned to receive either an ozonated oil-impregnated dressing or a standard sterile dressing after the operation. The main outcome is the level of wound inflammation measured on the third day after surgery. Other outcomes include wound temperature, pain levels, cosmetic healing, and wound-related problems during the first 30 days. The ozonated oil used in this study is a CE-certified medical product that is already used in routine wound care. This pilot study aims to provide preliminary data to help determine whether ozonated oil dressing may improve early wound healing compared with standard care.

Key facts

Study ID

NCT07328698

Run by

Nigde Omer Halisdemir University

People needed

60

Starts

2026-02-10

Expected to finish

2026-05-31

Last updated by the study team

2026-02-11

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged 18 to 75 years
• ASA physical status I-III
• Scheduled for elective, unilateral open inguinal hernia repair
• Able to provide written informed consent

You may not qualify if…

• Emergency inguinal hernia (incarcerated or strangulated)
• Recurrent inguinal hernia
• Concomitant surgical procedures during the same operation
• Immunosuppression or long-term systemic steroid use
• Use of anticoagulant or antiplatelet therapy
• Known bleeding disorders
• Active dermatologic disease at the surgical incision site
• Pregnancy

Where it is running

• Dr. Ali Rıza Erdoğan Private Practice Office — Niğde, Niğde Province, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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