The Efficacy of High-Power Laser Therapy in Meralgia Paresthetica

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Meralgia Paresthetica

In brief

The management of MP typically follows a conservative pathway, encompassing patient education, lifestyle modifications (e.g., avoidance of tight garments, weight loss), pharmacotherapy (such as neuropathic pain agents or corticosteroid injections), and physical therapy. However, evidence supporting the efficacy of these interventions is largely anecdotal or derived from low-quality studies, and a substantial proportion of patients experience persistent symptoms refractory to standard care. Therefore, the primary objective of this randomized, sham-controlled, assessor-blinded study is to investigate the efficacy of HPLT as an adjunct to standard conservative care on pain intensity, sensory symptoms, and functional capacity in patients with chronic Meralgia Paresthetica. The investigators hypothesize that patients receiving active HPLT will demonstrate significantly greater improvements in these outcomes compared to those receiving a sham laser procedure

Key facts

Study ID

NCT07328360

Run by

Uşak University

People needed

50

Starts

2026-01-12

Expected to finish

2026-08-05

Last updated by the study team

2026-01-13

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged 18-65 years.
• Clinical diagnosis of MP (based on history: burning pain, tingling, numbness in the lateral thigh; tenderness over the inguinal ligament near the anterior superior iliac spine (ASIS); and a positive pelvic compression test or Tinel's sign over the lateral femoral cutaneous nerve (LFCN)).
• Symptoms persistent for at least 3 months (chronic).
• A baseline pain intensity of ≥4 on the Numeric Rating Scale (NRS).

You may not qualify if…

• Secondary MP (e.g., due to pelvic surgery, trauma, or tumor mass effect confirmed by imaging).
• Significant lumbar radiculopathy (L1-L2).
• Coagulopathy, use of anticoagulants.
• Pregnancy.
• Skin disease or infection in the treatment area.
• Presence of a cardiac pacemaker.
• Severe cognitive impairment.

Where it is running

• Usak University — Uşak, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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