Intravenous Lidocaine Infusion Versus Intravenous Dexmedetomidine Infusion During Sleeve Gastrectomy
Recruiting now · Not applicable
Conditions studied: Bariatric Surgery, Lidocaine, Dexmedetomidine
In brief
Although laparoscopic (LAP) bariatric surgery is minimally invasive. Following any laparoscopic procedure, patients typically experience the peak of postoperative pain within the first 24 hours. This intense pain gradually subsides, with significant relief usually occurring by the 2nd or 3rd postoperative day. The initial peak and subsequent decline in pain intensity highlight the importance of effective early pain management strategies to ensure patient comfort and recovery during this critical period. Inadequate management of postoperative pain can result in serious complications. Lidocaine is increasingly recognised as a vital adjunct in managing perioperative pain. Its efficacy extends beyond traditional local anaesthetic applications, as it also demonstrates analgesic, anti-hyperalgesic, and anti-inflammatory properties. Dexmedetomidine is a highly selective alpha-2 adrenergic agonist with hypnotic, sedative, anxiolytic, sympatholytic, and analgesic effects, while causing minimal respiratory depression
Key facts
- Study ID
- NCT07327905
- Run by
- Alexandria University
- People needed
- 40
- Starts
- 2025-12-26
- Expected to finish
- 2026-11-01
- Last updated by the study team
- 2026-01-08
Who can join
Age: 20 and older, up to 50. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Age: 20-50 years, both sexes.
- American Standards Association (ASA) physical status class II to III.
- Body mass index (BMI) 35-50 kg m-².
You may not qualify if…
- Cardiac conduction disorders.
- Cardiomyopathy.
- Chronic opioid use.
- Allergy to the studied medications.
- Pregnancy and breastfeeding.
Where it is running
- Alexandria University — Alexandria, Egypt (enrolling)
Full record on ClinicalTrials.gov
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