Assessment of a Portable Digital Device for Quantified Analysis of Markerless Walking in Volunteers With Neuromuscular Diseases or Asymptomatic Volunteers

Recruiting now · Not applicable

Conditions studied: Spinal Muscular Atrophy (SMA), Charcot-Marie-Tooth, Muscular Dystrophy, Myotonic Dystrophy

In brief

In recent years, knowledge of neuromuscular diseases has advanced considerably, and new therapeutic avenues are beginning to emerge. The proliferation of clinical trials has created a need to identify biomarkers that are both sensitive to changes and specific to the disease. Current gait tests only consider the time factor and not the evolution of the patient's biomechanics, which may prove insufficient for patients whose symptoms generally progress slowly. Quantifying gait parameters in neuromuscular patients therefore appears necessary. This is why we propose to study markerless gait analysis in this population, which would allow for simple and effective monitoring of kinematic parameters without resorting to complex equipment incompatible with routine clinical practice.

Key facts

Study ID

NCT07321977

Run by

Institut de Myologie, France

People needed

30

Starts

2026-03-03

Expected to finish

2027-01-06

Last updated by the study team

2026-05-19

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may not qualify if…

• All volunteers
• Individuals under guardianship, curatorship, or legal protection
• Pregnant or breastfeeding women
• Non-ambulatory individuals
• Individuals with epilepsy
• Skin conditions preventing the placement of VICON motion sensors
• Asymptomatic volunteers
• Unstable respiratory or cardiac problems
• Neurological, musculoskeletal, or psychiatric problems
• Volunteers with a neuromuscular disease
• Recent trauma or serious falls (≤ 6 months)
• Individuals who have fallen more than twice in the past year and at least once in the past three months
• Use of assistive devices such as rigid knee braces or walkers
• Unstable cardiomyopathy
• Individuals awaiting diagnosis
• Exclusion criteria
• Inability to comply with the protocol requirements
• Medical or social conditions that could interfere with the study, as determined by the coordinating investigator or co-investigators.

Where it is running

• Centre d'Exploration et d'Évaluation Neuromusculaire — Paris, France (enrolling)

Full record on ClinicalTrials.gov

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