Evaluation of Emotion-related Salivary Molecular Biomarkers

Recruiting now · Has a placebo group

Conditions studied: Emotion

In brief

Recent studies show that emotional states can be discriminated by physiological responses. This physiological regulation results from the action of enzymes and hormones that represent the activity of the autonomic nervous system. The measurement of specific biomarkers, using non-invasive biological tests in saliva, would therefore provide physiological data on an individual's emotional state in response to stimuli, particularly olfactory stimuli.

Key facts

Study ID

NCT07320040

Run by

Sys2Diag

People needed

240

Starts

2022-11-14

Expected to finish

2027-06-14

Last updated by the study team

2026-01-29

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Subject willing to follow study procedures
• Subject able to understand the purpose, nature and methodology of the study
• Subject has signed informed consent form
• Subjects between 18 and 60 years of age.

You may not qualify if…

• Subjects deprived of liberty, protected adults, vulnerable persons or minors
• Subjects with a proven or suspected chronic infectious disease that could entail a risk of contamination during sample handling (laboratories not equipped to handle this type of sample)
• Rejection to sign the consent form.
• Non specific inclusion criteria:
• Pregnant or breastfeeding women
• Subjects presenting anosmia during the last 15 days
• Subjects presenting symptoms and signs of active oral inflammation, advanced periodontitis or severe gingivitis.

Where it is running

• SYS2DIAG - UMR9005 CNRS/ALCEN, Montpellier, 34184 — Montpellier, France (enrolling)

Full record on ClinicalTrials.gov

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