The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study

Recruiting now

Conditions studied: Rheumatoid Arthritis (RA, Atherosclerotic Cardiovascular Disease (ASCVD)

In brief

Individuals with rheumatoid arthritis (RA) have up to 2x the risk of having a heart attack compared to someone without RA. The goal of this study is to identify biomarkers that can help us do a better job of identifying individuals at risk before they develop symptoms of heart disease and start preventative treatment earlier.

Key facts

Study ID

NCT07315997

Run by

Brigham and Women's Hospital

People needed

120

Starts

2024-09-04

Expected to finish

2028-03-04

Last updated by the study team

2026-07-14

Who can join

Age: 35 and older, up to 79. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• RA diagnosed by a rheumatologist
• Age 40- 79
• ≥1 ASCVD risk factor including prediabetes, hypertension, BMI >30, current or history of cigarette smoking

You may not qualify if…

• Patients on a statin or with a contraindication to statin, on a cholesterol absorption inhibitor, or on a PCSK9 inhibitor
• Patients with diabetes mellitus
• Pregnancy

Where it is running

• Massachusetts General Hospital: Rheumatology — Boston, Massachusetts, United States (enrolling)
• Brigham and Womens Hospital — Boston, Massachusetts, United States (enrolling)
• Brigham and Women's Faulkner Hospital — Boston, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

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