Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) in Gastric Cancer
Recruiting now
Conditions studied: Gastric Cancer (GC), HIPEC, Peritoneal Metastases From Gastric Cancer, Hyperthermic Intraperitoneal Chemoperfusion
In brief
The study investigates the outcomes of hyperthermic intraperitoneal chemoperfusion (HIPEC) in combination with curative-intent gastrectomy in resectable locally-advanced and limited-metastatic (low peritoneal cancer index) gastric cancer.
Key facts
- Study ID
- NCT07313579
- Run by
- Ukrainian Society of Clinical Oncology
- People needed
- 200
- Starts
- 2025-12-01
- Expected to finish
- 2035-12-01
- Last updated by the study team
- 2026-01-13
Who can join
Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age 18-80
- Hystologicaly proven gastric adenocarcinoma
- ECOG status 0-1
- Written consent to participate in the study
- Medically and technically operable gastric tumor
- Only T4a or T4b tumours with any peritoneal cytology status
- Cytologically positive peritoneal washings (cyt+) with any T and N criteria
- Adequate haemopoetic, renal and hepatic function (Hb > 120, PLT > 150*10\^9/l, ALT < 60, AST <40, total bilirubin < 21 µmol/l, Creatinine clearance (male - 90-140, female - 80-130 ml/min)
You may not qualify if…
- Pregnancy/breastfeeding
- ECOG status 2-4
- Concomitant malignancy
- Mitomycin and/or Cisplatin hypersensitivity
- Uncontrollable chronic diseases
- Patients with coexisting malignancy other than basal cell carcinoma of the skin within the last five years.
- Presence of metastases other than regional or peritoneal (such as liver, lungs, bone, brain, distant lymph nodes)
- History of allergic reactions associated with cisplatin and Mitomycin C
- Patients with psychiatric illness/social situations with impaired compliance
- •Refusal to participate
Where it is running
- National Cancer Institute (NCI) — Kyiv, Ukraine (enrolling)
Full record on ClinicalTrials.gov
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