The Ultrasonographic Evaluation of Abdominal Accessory Respiratory Muscle Thickness in Patients With Parkinson's Disease: Correlation With Disease Severity and Expiratory Respiratory Muscle Strength

Recruiting now

Conditions studied: Parkinson Disease (PD), Maximum Inspiratory Pressure, Maximum Expiratory Pressure, Abdominal Accessory Respiratory Muscle Thickness

In brief

Parkinson's disease is a neurodegenerative disorder characterized by both motor and non-motor symptoms. The involvement of respiratory muscles can lead to impairments in respiratory function in these patients. In this study is to evaluate the thickness of abdominal accessory respiratory muscles using ultrasonography in patients with Parkinson's disease. Additionally, the relationship between disease severity and expiratory respiratory muscle strength will be examined. The study will include Parkinson's patients at different stages of the disease, with respiratory muscle thickness measured via ultrasonography. The collected data will then be compared with disease severity and expiratory muscle strength.

Key facts

Study ID

NCT07308795

Run by

Istanbul Physical Medicine Rehabilitation Training and Research Hospital

People needed

36

Starts

2025-12-29

Expected to finish

2026-04-20

Last updated by the study team

2026-01-02

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age > 18 years
• Parkinson's disease diagnosis with Modified Hoehn and Yahr stages 1-2-3
• Mini-Mental State Examination (MMSE) score > 23
• Body Mass Index (BMI) < 30

You may not qualify if…

• Active smokers
• Individuals with a diagnosis of active chest disease
• Those with hemodynamic instability
• Individuals with unstable vital signs
• Parkinson's patients who cannot be controlled with medical treatment
• Parkinson Plus syndromes

Where it is running

• İstanbul Fizik Tedavi Ve Rehabilitasyon Eğitim Ve Araştirma Hastanesi — Istanbul, BAHÇELİEVLER, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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