Comparison Between Two Methods for Renal Stone Treatment Mini Percutaneous Nephrolithotomy and Flexible Ureteroscopy With Suction Sheath

Recruiting now · Not applicable

Conditions studied: Stone;Renal, Stone, Urinary, Stone, Kidney, Stone Clearance

In brief

This study aims to compare the efficacy and safety of two modern, minimally invasive surgical techniques for the removal of kidney stones: Mini-Percutaneous Nephrolithotomy (Mini-PCNL) and Flexible Ureteroscopy (FURS) with Flexible and navigable suction sheath The primary objective is to determine which procedure results in a higher stone-free rate, as measured by post-operative imaging. Secondary objectives include comparing operative time, hospitalization length andcomplication rates between the two treatment groups. Patients with two to three centimeter kidney stones who are candidates for either procedure will be randomly assigned to undergo either Mini-PCNL or suctioning FURS. The outcomes will be critically assessed to help establish a higher level of evidence for guiding surgical management of kidney stones.

Key facts

Study ID

NCT07306819

Run by

Ain Shams University

People needed

120

Starts

2025-10-15

Expected to finish

2026-09-15

Last updated by the study team

2025-12-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patients aging 18 years old or more.
• Patients with renal stones between 2-3 cm in size confirmed by CT scan.

You may not qualify if…

• Patients with previous ureteric injury.
• Patients with uncontrolled diabetes mellitus or hypertension.
• Patients with uncontrolled hepatic dysfunction.
• Patients with uremia or renal failure.
• Pregnant patients.
• patients with active urinary tract infection.
• Patients with bleeding tendency or uncontrolled coagulopathy.
• Patients with congenital anomalies as horse-shoe kidney and pelvi-ureteric junction obstruction.

Where it is running

• Ain shams university hospitals — Cairo, Egypt (enrolling)

Full record on ClinicalTrials.gov

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