Cardiac Index-Guided Intraoperative Hemodynamic Management in Pediatric Moyamoya Surgery

Recruiting now · Not applicable

Conditions studied: Moyamoya Disease

In brief

This prospective randomized controlled trial evaluates whether individualized cardiac index-guided intraoperative hemodynamic management reduces postoperative transient ischemic episodes in pediatric patients undergoing encephaloduroarteriosynangiosis (EDAS) for Moyamoya disease. Patients are randomized 1:1 to goal-directed fluid therapy based on baseline cardiac index versus standard arterial pressure-based management. The primary outcome is the incidence of transient ischemic episodes during hospitalization.

Key facts

Study ID

NCT07304947

Run by

Seoul National University Hospital

People needed

94

Starts

2025-12-02

Expected to finish

2029-01-31

Last updated by the study team

2025-12-26

Who can join

Age: 0 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Pediatric patients <18 years undergoing EDAS for Moyamoya disease under general anesthesia

You may not qualify if…

• ASA physical status 4-5
• Emergency surgery
• Known cardiovascular disease
• Any condition judged inappropriate by investigators

Where it is running

• Seoul National University Children's Hospital — Seoul, South Korea (enrolling)

Full record on ClinicalTrials.gov

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