Evaluation of Effectiveness of Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy for Treatment of Chemotherapy Induced Peripheral Neuropathy
Recruiting now
Conditions studied: Chemotherapy Induced Peripheral Neuropathy (CIPN), Neuropathic Pain
In brief
The goal of this observational study is to learn about the effectiveness of closed-loop spinal cord stimulation (CL-SCS) therapy for treatment of painful chemotherapy induced peripheral neuropathy. The closed-loop SCS (CL-SCS) system stimulates the nerves in the spinal cord, measures their responses and automatically adjust the stimulation level accordingly in real time for each delivered pulse.
Key facts
- Study ID
- NCT07304401
- Run by
- Rijnstate Hospital
- People needed
- 20
- Starts
- 2025-12-01
- Expected to finish
- 2028-12-01
- Last updated by the study team
- 2025-12-26
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may not qualify if…
- Patient refusal to be included in study
- Patients unwilling or mentally incapable to complete the study questionnaires
- Other causes of neuropathy (for example diabetic- or small fiber neuropathy)
- Previous treatment with SCS for CIPN
- Presence of another pain syndrome unrelated to CIPN
- History of lower limb amputation or ulceration
- Body mass index (BMI) ≥ 40
- Severe psychiatric or neurological disorders
- Any other contra indication for locoregional anaesthesia
Where it is running
- Rijnstate Hospital — Arnhem, Netherlands (enrolling)
- Sint Antonius Ziekenhuis — Nieuwegein, Netherlands (enrolling)
- Bravis Hospital — Roosendaal, Netherlands (enrolling)
- ETZ — Tilburg, Netherlands (enrolling)
- ASZ — Zwijndrecht, Netherlands (enrolling)
Full record on ClinicalTrials.gov
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