Female Concussion Head Cooling
Starting soon · Not applicable
Conditions studied: Concussion (Diagnosis), Concussion Post Syndrome, Concussion, Mild
In brief
This research is being done to examine the benefits of a 28 day head cooling intervention on cognition, inflammation of the brain, sleep quality, menstrual symptom interaction, and mood in acutely concussed females. Brain cooling has been shown to cause temporary symptom relief after traumatic brain injury, but its implications for decreasing timeline of full concussion recovery, particularly in females during periods of confounding neuropsychological menstrual symptoms, remains unexplored.
Key facts
- Study ID
- NCT07303933
- Run by
- Penn State University
- People needed
- 32
- Starts
- 2026-01-15
- Expected to finish
- 2027-01-01
- Last updated by the study team
- 2025-12-26
Who can join
Age: 18 and older, up to 27. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- Require that any participant is 18-27 years old
- Require that participants be English speakers
- Require that participants are females
- Require that persons be able to provide consent for themselves
You may not qualify if…
- Exclude persons under 18 years old or over 27 years old
- Exclude persons taking anti-inflammatory drugs (both prescription and OTC), or those who will have taken them within 24 hours prior to Visit 1
- Exclude smokers and former smokers, as defined by CDC. (Anyone who smokes daily or who has smoked at least 100 cigarettes in their lifetime)
- Those with scalp infections, sun burns, skin cancers, and/or prior surgical scars should not participate
- Those with presence of an active infection (including a dental infection)
- Exclude persons who have migraines
- Exclude persons taking mood stabilizer medications
- Exclude persons who have consumed alcohol within 48 hours prior to study participation.
- Exclude persons who are males
Where it is running
- Recreation Building — University Park, Pennsylvania, United States
Full record on ClinicalTrials.gov
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