Non-invasive Assessment of Liver Fibrosis in a French Cohort of Pediatric Patients With Type III Glycogen Storage Disease: Current State and Perspectives

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Conditions studied: Liver Fibrosis

In brief

Patients with type III glycogen storage disease (GSDIII) can develop liver fibrosis, which can be complicated by liver failure or even hepatocellular carcinoma. Since the beginning of the 21st century, non-invasive techniques for assessing fibrosis, such as liver elastography, have been developed. These techniques often make it possible to avoid liver biopsies during patient follow-up and have already been validated in the management of several diseases in adults. These techniques are also beginning to be recommended for monitoring certain chronic liver diseases in children.

Key facts

Study ID

NCT07303140

Run by

University Hospital, Strasbourg, France

People needed

30

Starts

2024-10-18

Expected to finish

2026-02-01

Last updated by the study team

2025-12-24

Who can join

Age: 0 and older, up to 21. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Minors: from birth to 17 years
• Adults: 18 to 21 years
• Subjects being monitored for type III glycogen storage disease and having had at least one liver elastography measurement during their follow-up.

You may not qualify if…

• Patients monitored for type III glycogen storage disease but who had never undergone liver elastography during their follow-up.

Where it is running

• Service de pédiatrie 1 - CHU de Strasbourg - France — Strasbourg, France (enrolling)

Full record on ClinicalTrials.gov

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