AI-Assisted Relaxation and Breathing Training in Postmenopausal Women

Recruiting now · Not applicable

Conditions studied: Postmenopausal Period, Postmenopausal Women

In brief

This study aims to evaluate the effectiveness of relaxation and breathing training delivered by a physiotherapist and by an artificial intelligence-assisted system in postmenopausal women with non-specific chronic musculoskeletal pain. Menopause and the postmenopausal period are associated with decreased estrogen levels, structural and functional changes in the musculoskeletal system, increased pain prevalence, reduced muscle function, and impaired quality of life. Relaxation techniques, breathing-focused exercises, and mind-body practices have been shown to reduce pain, improve psychological well-being, and enhance sleep quality. With the growing use of digital health technologies, AI-supported relaxation training may offer personalized guidance, easy accessibility, and sustainable home-based practice, although its effectiveness in postmenopausal women has not yet been demonstrated. In this three-arm randomized controlled trial, participants will be assigned to physiotherapist-led relaxation and breathing training, AI-assisted relaxation and breathing training, or a control group. Interventions will last eight weeks and include sessions three days per week, each approximately 30 minutes. The physiotherapist-guided group will perform sessions face-to-face, while the AI-assisted group will complete prerecorded relaxation and breathing exercises created with AI-generated scripts and voice recordings. The control group will continue daily routines without structured training during the study period. Assessments will be conducted at baseline and at the end of eight weeks. Outcome measures will include pain severity, pressure pain threshold, musculoskeletal symptoms, menopause-specific quality of life, psychological status, sleep quality, dyspnea, and participant satisfaction. The study aims to compare the effects of physiotherapist-led and AI-assisted training modalities on pain, musculoskeletal health, sleep, psychological well-being, and quality of life. Findings are expected to contribute to the development of accessible and cost-effective interventions that support symptom management and improve the daily functioning of postmenopausal women.

Key facts

Study ID: NCT07302750
Run by: Baskent University
People needed: 48
Starts: 2026-04-01
Expected to finish: 2027-02-01
Last updated by the study team: 2026-06-10

Who can join

Age: 45 and older, up to 65. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

Women aged 45 to 65 years
Being in natural menopause (no menstrual bleeding for at least 12 months)
Having non-specific chronic musculoskeletal pain for at least 3 months (reporting a pain intensity of at least 4 cm on the VAS)
Using only standard analgesic medications for pain management
Being literate
Owning a smartphone or tablet, having the ability to listen to audio recordings, and having adequate skills to participate in online sessions
Being willing to participate in the study and providing written informed consent

You may not qualify if…

Surgical or medication-induced menopause
Regular use of opioid analgesics, anticonvulsants, antidepressants, or similar medications
Uncontrolled advanced cardiovascular, oncological, metabolic, rheumatologic, or neurological diseases
Body Mass Index (BMI) of 40 kg/m² or higher
History of major surgery or severe trauma within the past 3 months

Where it is running

Baskent University, Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Cardiopulmonary Rehabilitation Unit — Ankara, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.