Study of a Cohort of Non-HIV Immunocompromised Patients With Toxoplasmosis at the Strasbourg University Hospital

Recruiting now

Conditions studied: Cerebral Toxoplasmosis

In brief

Toxoplasmosis in HIV-positive individuals is well-studied and has a codified management protocol, which is not the case for other immunodeficiencies, except for recent recommendations in the context of hematopoietic stem cell transplantation. A description of this population is necessary to estimate the number of patients affected and to define their specific management (diagnosis, treatment, prevention).

Key facts

Study ID

NCT07299500

Run by

University Hospital, Strasbourg, France

People needed

30

Starts

2025-02-02

Expected to finish

2026-02-25

Last updated by the study team

2025-12-23

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult (≥18 years)
• Immunocompromised (i.e., solid organ transplant recipient, hematological malignancy, cancer patient, patient treated with immunosuppressive therapy or therapy affecting the immune system by any mechanism, hematopoietic stem cell transplant recipient, patient with an autoimmune disease or immunodeficiency, whether primary or secondary).
• At least one positive toxoplasmosis PCR test (regardless of tissue)

You may not qualify if…

• Subject who has expressed opposition to the reuse of their data for scientific research.
• HIV positive
• Congenital toxoplasmosis
• Isolated ocular toxoplasmosis in immunocompetent individuals

Where it is running

• Service d'immunologie clinique - Hôpitaux Universitaires de Strasbourg — Strasbourg, France (enrolling)

Full record on ClinicalTrials.gov

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