The Effective Blood Concentration of Ciprofol

Recruiting now

Conditions studied: Thyroid Disease

In brief

1. Eligible patients were selected and enrolled in the study. 2. General anesthesia was induced using ciprofol in all participants, with standardized evaluation of consciousness levels during induction. 3. The patients' pain and cognition are followed up after surgery.

Key facts

Study ID

NCT07294989

Run by

Peking University Shenzhen Hospital

People needed

101

Starts

2025-07-01

Expected to finish

2026-06-30

Last updated by the study team

2026-01-06

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients aged 18-65 years
• Scheduled for elective thyroidectomy
• ASA physical status classification I-II
• Willing to participate and providing written informed consent

You may not qualify if…

• Recent use of sedatives or opioid analgesics
• Severe hepatic or renal dysfunction defined as:Child-Pugh class C (score ≥10), Creatinine clearance <35 mL/min ,Requiring preoperative dialysis
• Significant cardiovascular comorbidities
• Body mass index ≥35 kg/m² or <18.5 kg/m²
• Known hypersensitivity or adverse reactions to propofol/ciprofol
• Neuropsychiatric disorders including:Alzheimer's disease,History of cerebrovascular events,Traumatic brain injury,Space-occupying brain lesions,Other significant neurological deficits

Where it is running

• Peking University Shenzhen Hospital — Shenzhen, Guangdong, China (enrolling)

Full record on ClinicalTrials.gov

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