Infusion of Lidocaine and Steroids in Middle Meningeal Artery for Pain in Subarachnoid Hemorrhage

Recruiting now · Phase 2

Conditions studied: Subarachnoid Hemorrhage, Aneurysmal, Headache, Opiate Dependence, Opioid Use

In brief

The goal of this clinical trial is to learn if an infusion of lidocaine, with or without steroids, into the middle meningeal artery (MMA) helps relieve severe headaches in patients with spontaneous subarachnoid hemorrhage (SAH). It will also study the safety of this treatment.

Key facts

Study ID

NCT07294118

Run by

The University of Texas Medical Branch, Galveston

People needed

15

Starts

2026-01-02

Expected to finish

2027-08-01

Last updated by the study team

2026-01-09

Who can join

Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥18 years.
• Diagnosed with aneurysmal SAH, Hunt and Hess Grades 1-2.
• Consent to study procedures and follow-up evaluations.

You may not qualify if…

• Known allergies to lidocaine or steroids.
• Arteriovenous malformations.
• Dural Arteriovenous Fistulas.
• Other significant intracranial pathologies.
• Hemodynamic instability preventing safe intervention.
• Previous MMA interventions.
• Previous craniotomies or need for craniotomy.
• Need for external ventricular drain.

Where it is running

• University of Texas Medical Branch, Galveston — Galveston, Texas, United States (enrolling)

Full record on ClinicalTrials.gov

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