Effects of the Dietary Inflammatory Index on Systemic Inflammation Markers and Gastrointestinal Symptoms in Individuals With Bariatric Surgery
Enrolling by invitation
Conditions studied: Bariatric Surgery, Bariatric Sleeve Gastrectomy, Inflamation, Systemic Inflammation, Dietary Inflammatory Index (DII), Systemic Inflammation Markers
In brief
The goal of this observational cross-sectional study is to evaluate the relationships between the Dietary Inflammatory Index (DII), systemic inflammatory markers, and gastrointestinal symptoms in adults aged 18-65 who have undergone bariatric surgery. The main questions it aims to answer are: Does the inflammatory potential of the diet affect systemic inflammation levels (such as SII, CRP, and WBC) in the post-operative period? Is there an association between the DII score and gastrointestinal symptoms (e.g., bloating, gas, abdominal pain)? Participants who are at least three months post-bariatric surgery will provide dietary intake data to calculate DII scores, undergo blood tests to measure inflammatory markers, and complete assessments regarding their gastrointestinal symptoms.
Key facts
- Study ID
- NCT07293624
- Run by
- Istanbul Bilgi University
- People needed
- 70
- Starts
- 2025-12-01
- Expected to finish
- 2026-07-30
- Last updated by the study team
- 2026-07-10
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adult individuals between the ages of 18 and 65,
- Having undergone bariatric surgery at least 3 months prior,
- Individuals who agreed to participate voluntarily in the study and signed the informed consent form,
- Having the cognitive ability/literacy to completely complete the food consumption record and questionnaire forms,
- Individuals with no health conditions that would prevent blood tests,
- Individuals who were regularly followed up after surgery and had no postoperative complications.
You may not qualify if…
- Individuals diagnosed with gastrointestinal diseases such as inflammatory bowel disease, celiac disease, or short bowel syndrome before or after bariatric surgery,
- Those with a history of diseases that could affect systemic inflammation, such as autoimmune disease, active infection, or cancer,
- Individuals regularly taking medications that could affect inflammation levels, such as corticosteroids, immunosuppressants, or anti-inflammatory drugs,
- Individuals actively or recently using probiotic supplements,
- Pregnant or breastfeeding women,
- Those with a history of chronic alcohol use or substance abuse,
- Individuals who experienced serious postoperative complications after surgery (e.g., anastomotic leak, serious infection, or conditions requiring reoperation),
- Individuals with cognitive or communication disabilities that prevented them from providing the necessary information and data to the study or who were lost to follow-up,
- Individuals with chronic organ failure,
- Individuals with a psychiatric diagnosis,
- Individuals who did not consent to their data being used for scientific purposes.
Where it is running
- Istanbul Bilgi University — Istanbul, Uskudar, Turkey (Türkiye)
Full record on ClinicalTrials.gov
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