Doppler Evaluation for Congestive Acute Kidney Injury in Critical Illness

Starting soon · Not applicable

Conditions studied: Acute Kidney Injury, VExUS

In brief

This study will evaluate the use of the Venous Excess Ultrasound (VExUS) score to guide fluid management in critically ill ICU patients through a prospective, multi-aim design combining observational and randomized components. The study will be conducted in the medical intensive care unit (MICU), multidisciplinary critical care unit (MCCU), and cardiac care unit (CCU) at UAB.

Key facts

Study ID

NCT07291778

Run by

University of Alabama at Birmingham

People needed

100

Starts

2026-12-01

Expected to finish

2028-12-01

Last updated by the study team

2026-07-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults (≥18 years old)
• Admitted to the MICU, MCCU, or CCU within 24 hours of admission
• Acute kidney injury (AKI) (based on Kidney Disease: Improving Global Outcomes (KDIGO) criteria)
• Adequate acoustic windows for a complete VExUS scan

You may not qualify if…

• < 18 years old
• pregnant women
• End-stage renal disease (ESRD) or prior renal transplant
• Acute tubular necrosis (ATN) defined by urinalysis (≥2+ protein, ≥2+ blood, ≥1 muddy brown cast, ≥1 RBC cast, or ≥1 dysmorphic RBC)'
• Prior Whipple procedures
• currently incarcerated

Where it is running

• University of Alabama at Birmingham Medical Center — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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