A Study Evaluating BFB759 in Moderate to Severe Hidradenitis Suppurativa

Recruiting now · Phase 2/Phase 3 · Has a placebo group

Conditions studied: Hidradenitis Suppurativa (HS)

In brief

This is a double-blind, placebo-controlled study where subjects are participating for approximately 36 to 40 weeks. The study compares how well BFB759 works and how safe it is compared with a placebo.

Key facts

Study ID

NCT07287644

Run by

Bluefin Biomedicine, Inc.

People needed

210

Starts

2025-11-03

Expected to finish

2027-08-01

Last updated by the study team

2026-05-29

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Are adults (18 to 75 years) with a diagnosis of hidradenitis suppurativa for at least one year.
• Have moderate to severe disease not well controlled by systemic antibiotic treatment.
• Are willing to follow study instructions, attend regular visits, and avoid certain other medications during the study.

You may not qualify if…

• Have certain infections or other immune conditions.
• Recently used medications that could interfere with the study.
• Are pregnant or breastfeeding.

Where it is running

• Encino Research Center — Encino, California, United States (enrolling)
• Clinical Science Institute — Santa Monica, California, United States (enrolling)
• Skin Care Research — Boca Raton, Florida, United States (enrolling)
• Center for Skin Science and Innovation — Fort Lauderdale, Florida, United States (enrolling)
• Ziaderm Research LLC — North Miami Beach, Florida, United States (enrolling)
• Clinical Trials Management, LLC — Tampa, Florida, United States (enrolling)
• DelRicht Research — Atlanta, Georgia, United States (enrolling)
• Southeast Research Specialist LLC — Douglasville, Georgia, United States (enrolling)
• The Indiana Clinical Trials Center, PC — Plainfield, Indiana, United States (enrolling)
• DS Research of Kentucky — Louisville, Kentucky, United States (enrolling)
• Martha Stewart — Mandeville, Louisiana, United States (enrolling)
• Clinical Trials Management, LLC — Metairie, Louisiana, United States (enrolling)
• DelRicht Research — New Orleans, Louisiana, United States (enrolling)
• Oakland Hills Dermatology — Auburn Hills, Michigan, United States (enrolling)
• MI Skin Innovations — Northville, Michigan, United States (enrolling)
• DelRicht Research — Wildwood, Missouri, United States (enrolling)
• JDR Dermatology Research LLC — Las Vegas, Nevada, United States (enrolling)
• Skin Cancer and Dermatology Institute — Reno, Nevada, United States (enrolling)
• Schweiger Dermatology, PC — Hackensack, New Jersey, United States (enrolling)
• Equity Medical LLC — The Bronx, New York, United States (enrolling)
• Optima Research - Boardman — Boardman, Ohio, United States (enrolling)
• Apex Clinical Research Center, LLC — Canton, Ohio, United States (enrolling)
• Apex Clinical Research Center, LLC — Mayfield Heights, Ohio, United States (enrolling)
• UPMC Department of Dermatology — Pittsburgh, Pennsylvania, United States (enrolling)
• Saguaro Dermatology — Phoenix, Arizona, United States (enrolling)

Full record on ClinicalTrials.gov

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