Decompressive Laminectomy Versus Laminectomy With Transpedicular Fixation in Lumbar Spinal Stenosis

Recruiting now · Early Phase 1

Conditions studied: Lumbar Spinal Stenosis

In brief

Lumbar spinal stenosis is a condition where the spinal canal becomes narrowed and can cause symptoms such as back pain, numbness, leg pain, and difficulty walking. Surgery is often considered when symptoms do not improve with medical treatment. This study will compare two types of surgery used to treat lumbar spinal stenosis: decompressive laminectomy alone and decompressive laminectomy with transpedicular screw fixation. Patients will be randomly assigned to one of the two surgical options. The purpose of this study is to determine which approach provides better pain relief, improved function, fewer complications, and better spinal stability after surgery.

Key facts

Study ID

NCT07281625

Run by

Punjab Health Care Commission

People needed

60

Starts

2025-10-01

Expected to finish

2025-12-31

Last updated by the study team

2025-12-15

Who can join

Age: 30 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 30-60 years
• Diagnosis of lumbar spinal stenosis based on MRI criteria (anteroposterior canal diameter <10-15 mm or cross-sectional area <75-145 mm²)
• Multilevel disc herniation
• Degenerative disc disease with Pfirrmann grade 3-5 on T2-weighted MRI
• Failure of at least six weeks of conservative treatment

You may not qualify if…

• Previous history of lumbar spine surgery
• Spinal malignancy
• Congenital lumbar spinal stenosis, scoliosis, or kyphoscoliosis
• Lumbar spondylolisthesis grade 3-5
• Significant comorbidities including diabetes mellitus or ischemic heart disease

Where it is running

• Services Institute of Medical Sciences — Lahore, Punjab Province, Pakistan (enrolling)

Full record on ClinicalTrials.gov

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