Use of Preoperative Postbiotic Supplementation in Colorectal Cancer Surgery

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Cancer (Colon Cancer, Breast Cancer, Lymphoma, Chronic Lymphoma Leukemia, Multiple Myeloma)

In brief

The treatment of colorectal cancer, in the absence of metastases, is primarily based on surgical removal. Colorectal surgery, which involves resecting part of the intestine and restoring intestinal continuity, carries a risk of complications. This study aims to evaluate whether oral supplementation with a postbiotic at a dose of 900 mg for 7 days prior to surgery reduces the rate of postoperative complications.

Key facts

Study ID

NCT07268846

Run by

AC Camargo Cancer Center

People needed

164

Starts

2025-06-01

Expected to finish

2027-06-01

Last updated by the study team

2025-12-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Individuals diagnosed with malignant neoplasm of the large intestine, specifically adenocarcinoma.
• Patients over 18 years of age, of both sexes.
• Patients who agree to participate in the study and sign the informed consent form.

You may not qualify if…

• Emergency or urgent surgeries.
• Cytoreductive surgeries involving intraoperative intraperitoneal chemotherapy.
• Extended surgeries for the treatment of recurrent tumors.

Where it is running

• A.C.Camargo Cancer Center — São Paulo, São Paulo, Brazil (enrolling)

Full record on ClinicalTrials.gov

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