Comparative Effects of Sensory Augmentation and Neuromodulation on Enhancing Motor Recovery Among Stroke Survivors

Recruiting now · Not applicable

Conditions studied: Stroke (CVA) or Transient Ischemic Attack

In brief

This study aims to evaluate the effectiveness of two rehabilitation techniques-Sensory Augmentation (using mirror therapy) and Neuromodulation (using transcranial direct current stimulation, tDCS)-in improving motor recovery among stroke survivors. Stroke often results in long-term impairments, particularly in upper limb motor function, which is critical for daily activities. Although current rehabilitation strategies help, more effective solutions are needed to enhance recovery. Participants, aged 45-65 with chronic stroke and upper extremity impairments, will be randomized into three groups: Group 1 will receive a combination of sensory augmentation (mirror therapy) and neuromodulation (tDCS) with routine physical therapy; Group 2 will receive sensory augmentation (mirror therapy) with routine physical therapy; and Group 3 will receive neuromodulation (tDCS) with routine physical therapy. The interventions will take place four times a week for 8 weeks, and participants will undergo motor function assessments, including the Fugl-Meyer Assessment and Jebsen-Taylor Test, before and after the intervention. The study will compare the effects of each intervention on motor recovery, specifically focusing on upper limb function and motor control. The findings could lead to improved rehabilitation protocols, offering stroke survivors better therapeutic options and enhancing their quality of life.

Key facts

Study ID

NCT07266662

Run by

Lahore University of Biological and Applied Sciences

People needed

36

Starts

2025-11-25

Expected to finish

2026-05-30

Last updated by the study team

2025-12-17

Who can join

Age: 45 and older, up to 56. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age: 45-65
• Gender: both male and female
• Ischemic stroke
• Diagnosed cases of middle cerebral artery stroke by neurologist
• Stage of recovery - Chronic (more than 6 months)
• Burnstromm recovery stage 3
• Good Compliance

You may not qualify if…

• Vestibular Dysfunction
• Serious cognitive impairment,
• Severe vision or visuospatial neglect
• Spasticity (Modified Ashworth scale >3)
• Upper extremity contractures
• Upper extremity fractures
• Orthopedic disease
• Neurological conditions (other than stroke)
• Recurrence of stroke or epilepsy during the study period
• Serious systemic impairment or concomitant diseases
• Patients refused to participate in the experiment

Where it is running

• Pakistan Society of Rehabilitation and Differently Abled Hospital — Lahore, Punjab Province, Pakistan (enrolling)
• Lahore University of Biological and Applied Sciences — Lahore, Punjab Province, Pakistan

Full record on ClinicalTrials.gov

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