Building Adaptive School-based Interventions for Caries

Starting soon · Phase 3

Conditions studied: Dental Caries

In brief

Dental caries (tooth decay) is the world's most prevalent noncommunicable disease. Current preventive and therapeutic treatments are available that can be provided in a school-based health service environment. However, not all children respond to care, and school programs can result in under- or over-treatment, leaving children at high risk. The Building Adaptive School-based Interventions for Caries (BASICS) study will identify the optimal sequence and intensity of these treatments to minimize nonresponse, creating adaptive interventions tailored to specific needs in order to personalize school-based dental medicine.

Key facts

Study ID

NCT07265830

Run by

University of Pennsylvania

People needed

1200

Starts

2026-09-01

Expected to finish

2030-06-01

Last updated by the study team

2026-03-02

Who can join

Age: 5 and older, up to 13. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Be enrolled in participating schools
• Be between the ages of 5 and 13 years
• Provide parental/guardian informed consent
• Child assent

You may not qualify if…

• Ulcerative gingivitis or stomatitis
• Known sensitivity to silver or other heavy-metal ions
• More than six affected sites
• Those who have had full mouth gingivectomies
• Patients showing abnormal skin sensitization in daily circumstances
• Those who have had pulp capping

Full record on ClinicalTrials.gov

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