Cognitive Disparities in Parkinson's Disease

Completed

Conditions studied: Parkinson Disease

In brief

This study will investigate disparities in neurocognitive impairment (NCI) among Hispanics/Latinos/as/x (henceforth Hispanics) living in the US-Mexico borderland of California or in North Carolina with Parkinson's Disease (PD) and determine mechanisms underlying these disparities. NCI is an important aspect of the clinical course of PD, particularly among Hispanics, who have increased prevalence of dementia. Among the many potential factors driving this disparity, the investigators chose to focus on a modifiable risk factor to which Hispanics are particularly vulnerable, and that has been linked to increased NCI, namely cardiovascular (CVD) risk (e.g., diabetes, hypertension, obesity).

Key facts

Study ID

NCT07262658

Run by

Duke University

People needed

40

Starts

2022-09-30

Expected to finish

2025-12-31

Last updated by the study team

2026-01-15

Who can join

Age: 40 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 40 years old and older
• non-Hispanic Whites
• Hispanics
• All genders
• Ability to provide consent
• Diagnosed with Parkinson's Disease

You may not qualify if…

• Other neurological illness/diagnosis
• Injury that would affect cognition (i.e. stroke, closed head injury with loss of consciousness for longer than 30 minutes)

Where it is running

• UC San Diego — La Jolla, California, United States
• Duke University — Durham, North Carolina, United States

Full record on ClinicalTrials.gov

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