Epidemiology and Processes of Care for Renal Replacement Therapy in Acute Kidney Injury in Latin America

Recruiting now

Conditions studied: Dialysis, Critically Ill Acute Kidney Injury, Renal Replacement Therapy for Acute Kidney Injury in ICU, Acute Kidney Injury, Renal Replacement Therapy, AKI

In brief

This is an international, multicenter, observational study aimed at investigating acute kidney injury requiring renal replacement therapy (AKI-RRT) in Latin American countries. The main questions this study aims to answer are: * What is the epidemiology, outcomes, and processes of care for patients with AKI-RRT in Latin America? * How do outcomes differ across different countries in Latin America? * What factors (demographics, clinical, socioeconomic) influence outcomes in patients with AKI-RRT in Latin America? The main aims of this study are to: * Establish a comprehensive database containing clinical, laboratory, treatment, process, and outcome data of patients with AKI-RRT in Latin America * Describe current epidemiology of AKI-RRT in Latin America * Compare processes of care and outcomes across different countries in Latin America * Provide data resources to facilitate and promote clinical research in AKI-RRT

Key facts

Study ID

NCT07262320

Run by

University of Alabama at Birmingham

People needed

1000

Starts

2026-03-01

Expected to finish

2027-06-30

Last updated by the study team

2026-03-12

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult patient (≥18) admitted to the ICU
• First ICU admission during current hospitalization
• Diagnosis of acute kidney injury stage 3 according to KDIGO guidelines
• RRT initiated no earlier than 3 days before or no later than 7 days after ICU admission

You may not qualify if…

• Transfer from outside hospital with ongoing RRT
• RRT exposure of less than 2 days (if CRRT or PD was provided) or less than 2 HD/SLED sessions
• Kidney failure (ESRD) patients on maintenance dialysis
• Kidney transplant recipients
• Previous or new diagnosis of glomerulonephritis

Where it is running

• Hospital Nacional Arzobispo Loayza — Lima, Peru (enrolling)
• Fundación Cardioinfantil — Bogotá, Colombia (enrolling)
• Hospital San Jose de Popayan — Popayán, Colombia (enrolling)
• Hospital General de la Plaza de la Salud — Santo Domingo, Dominican Republic (enrolling)
• Hospital Civil de Guadalajara — Guadalajara, Mexico (enrolling)
• Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán — Mexico City, Mexico (enrolling)
• Hospital Universitario "José Eleuterio González" — Monterrey, Mexico (enrolling)
• Hospital Obrero No 2 — Cochabamba, Bolivia (enrolling)
• Ana Nery Hospital — Bahia, Brazil
• Hospital Sao Lucas da PUCRS — Porto Alegre, Brazil
• Hospital das Clínicas da Universidade de São Paulo — São Paulo, Brazil
• Hospital Las Higueras — Talcahuano, Chile
• DIALNEF — Quito, Ecuador
• Instituto Guatemalteco de Seguridad Social — Guatemala City, Guatemala
• Hospital General de México Dr Eduardo Liceaga — Mexico City, Mexico

Full record on ClinicalTrials.gov

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