Effects of Dexmedetomidine Target Controlled Infusion on Patient State Index Values and Electroencephalographic Spectrum During Total Intravenous Anesthesia With Propofol

Recruiting now

Conditions studied: Adjuvants, Anesthesia

In brief

Dexmedetomidine Target Controlled infusion (TCI, Dyck model) effects on Neuromonitoring during Total Intravenous Anesthesia (TIVA) with Propofol and Remifentanil TCI (Eleveld model) has not been investigate yet. Authors aim to investigate its effect on Patient State index (PSi), the power spectrum EEG, the Analgesia Nociception Index (ANI) and pupillometry values during maintenance during TIVA-TCI with Propofol, Remifentanil and Dexmedetomidine.

Key facts

Study ID

NCT07259460

Run by

University of Padova

People needed

60

Starts

2025-12-01

Expected to finish

2026-07-30

Last updated by the study team

2025-12-23

Who can join

Age: 18 and older, up to 80. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Undergo general anaesthesia with Targeted Controlled Infusion of Propofol and Rmifntanil (Eleveld model) and Dexmedetomidine (Dyck model)

You may not qualify if…

• Neurological disease
• Psychiatric disease
• Obesity
• Regional anesthesia performed

Where it is running

• Treviso Regional Hospital — Treviso, TV, Italy (enrolling)

Full record on ClinicalTrials.gov

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