Stress and Anxiety Effects on Valuation

Recruiting now · Not applicable

Conditions studied: Reward Value Level

In brief

The purpose of this study is to understand how stress, anxiety, and negative affect change learning and decision-making processes. The primary objective is to assess two forms of decision-making-reward adaptation and emotion prediction errors-differ as a function of stress and anxiety. The secondary objectives are to assess how individual differences measured in our studies relate to these decision variables.

Key facts

Study ID

NCT07252947

Run by

NYU Langone Health

People needed

200

Starts

2025-12-18

Expected to finish

2028-11-07

Last updated by the study team

2025-12-22

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Aims 1-3: To be eligible for participation in this study, an individual must meet all of the following criteria:
• 18-65 years of age
• Able to speak, read, and write fluently in English
• Be willing and able to follow study procedures and provide informed consent.
• Aim 4: To be eligible for participation in this study, an individual must meet all of the following criteria:
• 18-65 years of age
• Diagnosis of GAD
• Able to speak, read, and write fluently in English
• Be willing and able to follow study procedures and provide informed consent.

You may not qualify if…

• Aims 1-3: Individuals will be excluded from participation if any of the following criteria are met:
• History of or medication for neurologic or psychiatric disease
• High-blood pressure or heart condition
• Diabetes, food allergies, metabolic disorders or history of eating disorder
• Use of corticosteroids or beta-blockers
• Pregnancy
• Aim 4: Individuals will be excluded from participation if any of the following criteria are met:
• High-blood pressure or heart condition
• Diabetes, food allergies, metabolic disorders or history of eating disorder
• Use of corticosteroids or beta-blockers
• Lifetime history of bipolar disorder or any psychotic disorder; substance use disorder in past 3 months; eating disorder in past 6 months; current major depressive disorder (past is allowed)
• Active suicidal ideation with plan and intent (indicated by score >=4 on the Columbia Suicide Severity Scale)
• Not on stable dose of psychiatric medication for at least 4 weeks prior to study participation
• Pregnancy

Where it is running

• NYU Langone Health — New York, New York, United States (enrolling)

Full record on ClinicalTrials.gov

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