Self-Help Cognitive Processing Therapy (CPT)/Women Veterans Network (WoVeN) Study

Recruiting now · Not applicable

Conditions studied: Posttraumatic Stress Disorder, Depression

In brief

Posttraumatic stress disorder (PTSD) can have significant impairment on aspects of mental well-being (MWB) including functioning, loneliness, physical health, and quality of life. There are several evidence-based treatments (EBPs) effective in treating PTSD such as Cognitive Processing Therapy (CPT) which is a specific type of cognitive behavioral therapy that has been proven effective in reducing symptoms of PTSD. However, there are several barriers (e.g., lack of providers, waitlists, costs, stigma, disabilities that complicate travel) that can prevent someone from engaging with these treatments. Recently, a self-help version of CPT was created to help address these barriers; but little research has been conducted to test its efficacy. Further, less is know about how a peer support program may augment improvements from participating in an EBP. The Women Veteran Network (WoVeN), a peer support program designed for women veterans, has a manualized 8-week program that directly targets MWB. It has been found to help foster belongingness and connectedness, particularly in those suffering from PTSD and depression. The present study aims to establish the feasibility, acceptability and tolerability of a scalable, sustainable, and effective treatment option for trauma survivors with subthreshold or full PTSD. The overarching goal is to understand the effectiveness of a self-help version of an EBP (either alone or in combination with a peer support program) in reducing PTSD symptoms while also helping improve mental well-being, reduce barriers, and increase access to quality care within health disparity populations.

Key facts

Study ID

NCT07250061

Run by

Boston University

People needed

100

Starts

2026-03-05

Expected to finish

2028-03-01

Last updated by the study team

2026-05-27

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Identifies as a woman
• Has served in the United States military
• A full or subthreshold (meets criteria for 2 out of 4 of the symptom clusters for PTSD) Post Traumatic Stress Disorder (PTSD) diagnosis
• Able to read English well enough to complete study questionnaires

You may not qualify if…

• Clinician judgment that the participant is not appropriate for self-help level of care for PTSD (i.e., recent psychiatric hospitalization, requires detox, volatile, active suicidality)
• Current psychosis or unstable bipolar disorder (determined during baseline interview as described in screening and enrollment procedures)
• Must not have participated in a WoVeN group within the last year
• Must not be receiving an evidenced-based therapy for PTSD at the time of the screening

Where it is running

• Fully online study — Boston, Massachusetts, United States (enrolling)

Full record on ClinicalTrials.gov

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