Pilot Study, Aimed at Describing in Myography, the Collapse of the Muscular Response Visualized in the Scratch Collapse Test, in Carpal Tunnel Syndrome.

Recruiting now · Not applicable

Conditions studied: Carpal Tunnel Syndrome (CTS)

In brief

The Scratch Collapse Test (SCT) is a neurocutaneous reflex used to detect peripheral nerve compression in nerve tunnel syndromes. It first involves applying a sensory stimulus to the skin over the suspected nerve compression point, then bilaterally testing the strength of a specific muscle in the patient. Compression is then manifested by a transient loss of strength in the muscle on the affected side, while it is preserved on the healthy side. This loss of strength is transient and disappears after a few seconds. This test can be performed during a patient's clinical examination, with the physician assessing strength or, conversely, muscle collapse. However, while several articles have described the relevance of this test, as well as its sensitivity and specificity, no study has specifically investigated and measured this observed loss of eccentric muscle tone and its unilateral and transient nature, even though the phenomenon of CSP (cutaneous silent period) has been described. We therefore propose to analyze the myographic tracing obtained in patients diagnosed with unilateral carpal tunnel syndrome. A transient loss of muscle tone is expected by selective needle myography on the pathological side after cutaneous sensory stimulation of the wrist, while cutaneous sensory stimulation on the healthy side does not alter the tracings obtained by myography.

Key facts

Study ID

NCT07248124

Run by

Elsan

People needed

25

Starts

2025-11-04

Expected to finish

2026-05-05

Last updated by the study team

2025-11-25

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patient over 18 years old
• Patient with clinical unilateral carpal tunnel syndrome diagnosed by history, clinical examination and electromyography,
• Patient who has been informed and has given their free, informed, and written consent,
• Patient affiliated with or beneficiary of a social security scheme.

You may not qualify if…

• Other associated canal syndrome on either side (ulnar, defilement, lacertus),
• Rotator cuff pathology, insufficiency or rupture of the infraspinatus,
• Associated cervical pathology,
• Neuropathy, central or peripheral neurological disease,
• Diabetic patient,
• Patient with cognitive impairments that prevent the understanding of the study information,
• Refusal to participate in the study,
• Pregnant, parturient, or breastfeeding woman,
• Patient under legal protection,
• Patient not receiving health protection,
• Protected patient: adult under guardianship, curatorship, or other legal protection, deprived of liberty by judicial or administrative decision

Where it is running

• Clinique de l'Ormeau — Tarbes, France (enrolling)

Full record on ClinicalTrials.gov

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